The association between respiratory diseases and periodontitis: A systematic review and meta-analysis.
J Clin Periodontol
; 50(6): 842-887, 2023 06.
Article
in English
| MEDLINE | ID: covidwho-2192725
ABSTRACT
AIM:
To evaluate (1) whether periodontitis has an influence on the prevalence/incidence of respiratory diseases (chronic obstructive pulmonary disease [COPD], asthma, community-acquired pneumonia [CAP], obstructive sleep apnoea [OSA] and COVID-19), and (2) what is the impact of periodontal therapy on the onset or progression of respiratory diseases. MATERIALS ANDMETHODS:
An electronic search was performed on Pubmed, Cochrane Library and Scopus databases up to October 2021, to identify studies answering the PECOS and PICOS questions.RESULTS:
Seventy-five articles were selected. Meta-analyses identified statistically significant associations of periodontitis with COPD (nstudies = 12, odds ratio [OR] = 1.28, 95% confidence interval [CI] [1.16; 1.42], p < .001), and OSA (ns = 6, OR = 1.65, 95% CI [1.21; 2.25], p = .001), but not for asthma (ns = 9, OR = 1.53, 95% CI [0.82; 2.86], p = .181). For acute conditions, two studies were found for CAP, while for COVID-19, significant associations were found for the need of assisted ventilation (ns = 2, OR = 6.24, 95% CI [2.78; 13.99], p < .001) and COVID-related mortality (ns = 3, OR = 2.26, 95% CI [1.36, 3.77], p = .002). Only four intervention studies were found, showing positive effects of periodontal treatment on COPD, asthma and CAP.CONCLUSIONS:
A positive association between periodontitis and COPD, OSA and COVID-19 complications has been found, while there is a lack of intervention studies.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Periodontitis
/
Pneumonia
/
Asthma
/
Sleep Apnea, Obstructive
/
Pulmonary Disease, Chronic Obstructive
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
J Clin Periodontol
Year:
2023
Document Type:
Article
Affiliation country:
Jcpe.13767
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