Diffuse proliferative glomerulonephritis in a patient with COVID-19 infection.
BMJ Case Rep
; 16(1)2023 Jan 05.
Article
in English
| MEDLINE | ID: covidwho-2193662
ABSTRACT
COVID-19 primarily presents with respiratory involvement. Extrapulmonary manifestations as the sole manifestation also occur although rare. The kidney, being one of the organs with the greatest number of ACE receptors, is usually reported as part of multiorgan involvement. We report an early adolescent boy who presented with nephrotic-nephritic syndrome with severe kidney dysfunction from COVID-19 infection. He had low C3 and undetected antineutrophil cytoplasmic antibodies, antinuclear antibody and antistreptolysin O. Kidney biopsy revealed findings consistent with diffuse proliferative glomerulonephritis with a focal glomerular crescent formation and thin basement nephropathy. Due to the rapidly progressive deterioration of kidney function, he was given pulse methylprednisolone therapy followed by oral prednisone. Complete recovery was documented 12 weeks after the onset of post-infectious glomerulonephritis. The possible pathogenesis of glomerulonephritis in a patient with COVID-19, its differential diagnosis and treatment are discussed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Renal Insufficiency
/
COVID-19
/
Glomerulonephritis
/
Kidney Diseases
Type of study:
Case report
/
Diagnostic study
Topics:
Long Covid
Limits:
Adolescent
/
Humans
/
Male
Language:
English
Year:
2023
Document Type:
Article
Affiliation country:
Bcr-2022-251962
Similar
MEDLINE
...
LILACS
LIS