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Using an objective computer task (QbTest) to aid the identification of attention deficit hyperactivity disorder (ADHD) in the Children and Young People Secure Estate (CYPSE): a feasibility randomised controlled trial.
Chitsabesan, Prathiba; Hall, Charlotte Lucy; Carter, Lesley-Anne; Reeves, Mindy; Mohammed, Vaseem; Beresford, Bryony; Young, Susan; Kraam, Abdullah; Trowse, Sally; Wilkinson-Cunningham, Lloyd; Lennox, Charlotte.
  • Chitsabesan P; Children and Young People's Research Unit, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UK pchitsabesan@nhs.net.
  • Hall CL; Psychiatry, Institute of Mental Health, NIHR CLAHRC-East Midlands, Nottingham, UK.
  • Carter LA; Centre for Biostatistics, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Manchester, UK.
  • Reeves M; Medical School, The University of Manchester, Manchester, UK.
  • Mohammed V; Medical School, The University of Manchester, Manchester, UK.
  • Beresford B; Social Policy Research Unit, University of York, York, UK.
  • Young S; Department of Clinical and Forensic Psychology, Psychology ServicesLimited, London, UK.
  • Kraam A; Department of Psychology, University of Reykjavik, Reykjavik, Iceland.
  • Trowse S; Children and Adolescent Mental Health, Rotherham Doncaster and South Humber Mental Health NHS Foundation Trust, Doncaster, UK.
  • Wilkinson-Cunningham L; Child and Adolescent Mental Health Service, Pennine Care NHS Foundation Trust, Ashton-under-Lyne, UK.
  • Lennox C; Research andDevelopment, Leeds Community Healthcare NHS Trust, Leeds, UK.
BMJ Open ; 12(12): e064951, 2022 12 16.
Article in English | MEDLINE | ID: covidwho-2193783
ABSTRACT

OBJECTIVES:

QbTest has been shown to improve time to decision/diagnosis for young people with attention deficit hyperactivity disorder (ADHD). The aim was to assess the feasibility of QbTest for young people in prison.

DESIGN:

Single-centre feasibility randomised controlled trial (RCT), with 11 allocation. Concealed random allocation using an online pseudorandom list with random permuted blocks of varying sizes.

SETTING:

One Young Offenders Institution in England.

PARTICIPANTS:

355 young people aged 15-18 years displaying possible symptoms of ADHD were assessed for eligibility, 69 were eligible to take part and 60 were randomised. INTERVENTION QbTest-a computer task measuring attention, activity and impulsivity. MAIN OUTCOME

MEASURES:

Eligibility, recruitment and retention rates and acceptability of randomisation and trial participation.

RESULTS:

Of the 355 young people assessed for eligibility, 69 were eligible and 60 were randomised (n=30 QbTest plus usual care; n=30 usual care alone). The study achieved the specified recruitment target. Trial participation and randomisation were deemed acceptable by the majority of participants. 78% of young people were followed up at 3 months, but only 32% at 6 months, although this was also affected by COVID-19 restrictions. Secondary outcomes were mixed. Participants including clinical staff were mostly supportive of the study and QbTest; however, some young people found QbTest hard and there were issues with implementation of the ADHD care pathway. There were no serious adverse events secondary to the study or intervention and no one was withdrawn from the study due to an adverse event.

CONCLUSIONS:

With adaptations, a fully powered RCT may be achievable to evaluate the effectiveness of QbTest in the assessment of ADHD in the Children and Young People Secure Estate, with time to decision (days) as the primary outcome measure. However, further programme developmental work is required to address some of the challenges highlighted prior to a larger trial. TRIAL REGISTRATION NUMBER ISRCTN17402196.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / COVID-19 Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Limits: Adolescent / Child / Humans Language: English Journal: BMJ Open Year: 2022 Document Type: Article Affiliation country: Bmjopen-2022-064951

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Attention Deficit Disorder with Hyperactivity / COVID-19 Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Limits: Adolescent / Child / Humans Language: English Journal: BMJ Open Year: 2022 Document Type: Article Affiliation country: Bmjopen-2022-064951