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Studying C-reactive protein and D-dimer levels in blood may prevent severe complications: A study in Bangladeshi COVID-19 patients.
Sultana, Gazi Nurun Nahar; Srivastava, Anshika; Akhtaar, Khalida; Singh, Prajjval Pratap; Islam, Md Anarul; Mishra, Rahul Kumar; Chaubey, Gyaneshwer.
  • Sultana GNN; Centre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
  • Srivastava A; Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
  • Akhtaar K; Centre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
  • Singh PP; Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
  • Islam MA; Centre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
  • Mishra RK; Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
  • Chaubey G; Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
Front Genet ; 13: 966595, 2022.
Article in English | MEDLINE | ID: covidwho-2198785
ABSTRACT
The ongoing COVID-19 pandemic has been a scientific, medical and social challenge. Since clinical course of this disease is largely unpredictable and can develop rapidly causing severe complications, it is important to identify laboratory biomarkers, which may help to classify patient's severity during initial stage. Previous studies have suggested C-reactive protein (inflammatory) and D-dimer (biochemical) as an effective biomarker. The differential severity in patients across the world and our limited understanding in the progression of the disease calls for a multi-country analysis for biomarkers. Therefore, we have analyzed these biomarkers among 228 Bangladeshi COVID-19 patients. We observed significant association of COVID-19 severity with these two biomarkers. Thus, we suggest to use these biomarkers for Bangladeshi COVID-19 patients for better disease monitoring. Such validated preventive measures may decrease the case fatality ratio substantially.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Front Genet Year: 2022 Document Type: Article Affiliation country: Fgene.2022.966595

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Front Genet Year: 2022 Document Type: Article Affiliation country: Fgene.2022.966595