Alzheimer's disease risk after COVID-19: a view from the perspective of the infectious hypothesis of neurodegeneration.
Neural Regen Res
; 18(7): 1404-1410, 2023 Jul.
Article
in English
| MEDLINE | ID: covidwho-2201618
ABSTRACT
In light of the rising evidence of the association between viral and bacterial infections and neurodegeneration, we aimed at revisiting the infectious hypothesis of Alzheimer's disease and analyzing the possible implications of COVID-19 neurological sequelae in long-term neurodegeneration. We wondered how SARS-CoV-2 could be related to the amyloid-ß cascade and how it could lead to the pathological hallmarks of the disease. We also predict a paradigm change in clinical medicine, which now has a great opportunity to conduct prospective surveillance of cognitive sequelae and progression to dementia in people who suffered severe infections together with other risk factors for Alzheimer's disease.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Language:
English
Journal:
Neural Regen Res
Year:
2023
Document Type:
Article
Affiliation country:
1673-5374.360273
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