Antibody Responses of SARS-CoV-2 Vaccines amongst Health Care Workers in a Tertiary Care Hospital in Tripura, India: A Cross-Sectional Study.
Indian J Community Med
; 47(4): 583-586, 2022.
Article
in English
| MEDLINE | ID: covidwho-2201718
ABSTRACT
Background:
Vaccines against COVID-19 plays an important role in limiting the spread of SARS-CoV-2 infections and also in curbing mortality and morbidity due to COVID-19.Objective:
To estimate the anti-spike antibody response after receiving the second dose of SARS-CoV-2 vaccines amongst health care workers of a tertiary care hospital in Tripura, India. Materials andMethod:
A cross- sectional study was conducted from 1 July to 20 August 2021 at Agartala Government Medical College and GBP Hospital, Agartala among 561 health care workers who had received first and second doses of SARS-CoV-2 vaccines and had completed 14 days after receiving the second dose.Results:
The present study showed that health care workers who had received both doses of COVID-19 vaccine had 99.5% seropositivity to anti-spike antibody. The median SARS-CoV-2 anti-spike antibody titter was 250 with an IQR (211.55-250). Seropositivity rate was higher among Covishield recipients (99.8% [550/551]) as compared to Covaxin recipients (80% [8/10]) and it was found to be statistically significant (P = 0.000).Conclusion:
The present study suggests that a good immune response was elicited against spike antigen of SARS-CoV-2 after two complete doses of Covishield (ChAdOx1-nCoV-19) or Covaxin (BBV152).
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
/
Randomized controlled trials
Topics:
Vaccines
Language:
English
Journal:
Indian J Community Med
Year:
2022
Document Type:
Article
Affiliation country:
Ijcm.ijcm_71_22
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