Difficulties in diagnosis of SARS-CoV-2 myocarditis in an adolescent.
Swiss Med Wkly
; 152: w30214, 2022 07 18.
Article
in English
| MEDLINE | ID: covidwho-2202463
ABSTRACT
OBJECTIVES:
We present an adolescent with cardiogenic shock due to ventricular tachycardia 2 weeks after SARS-CoV-2 infection. Acute myocarditis or myocardial dysfunction is associated with SARS-CoV-2 infection, but diagnosis may be difficult, even including endomyocardial biopsy. CASE REPORT A 15-year-old healthy adolescent was admitted to our hospital 2 weeks after SARS-CoV-2 infection with cardiogenic shock due to ventricular tachycardia. After cardioversion, antiarrhythmic treatment, ventilation, and inotropic support, the severely reduced myocardial function recovered completely within 2 weeks. Cardiac magnetic resonance imaging and cardiac catheterisation including right ventricular endomyocardial biopsy revealed an increased number of CD68+ macrophages in the myocardium, but nested (RT-) polymerase chain reaction (PCR) investigations revealed no viral or bacterial DNA/RNA.DISCUSSION:
SARS-CoV-2 infection may be associated with myocarditis leading to life-threatening arrhythmia and severe myocardial systolic and diastolic dysfunction, which may be short lasting and completely recover. Although former SARS-Cov-2 infection might suggest SARS-CoV-2-associated myocarditis, definite histological diagnosis including nested PCR investigations remains difficult.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tachycardia, Ventricular
/
COVID-19
/
Myocarditis
Type of study:
Case report
/
Diagnostic study
Limits:
Adolescent
/
Humans
Language:
English
Journal:
Swiss Med Wkly
Journal subject:
Medicine
Year:
2022
Document Type:
Article
Affiliation country:
SMW.2022.w30214
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