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Clinical features and outcomes of COVID-19 patients with cardiac disease: Single center experience
Anatolian Journal of Cardiology ; 25(Supplement 1):S91-S92, 2021.
Article in English | EMBASE | ID: covidwho-2202566
ABSTRACT
Background and

Aim:

Comorbidities accompany the majority of COVID-19 patients. Studies have shown that between 15% and 40% of them have a history of heart disease, and it has been reported that the course of the disease is more severe in those with heart disease.The aim of our study is to compare the clinical presentations and outcomes of patients with and without cardiac disease hospitalized for COVID-19 infection and to share our single center experience. Method(s) 184 COVID-19 patients who were admitted to Antalya Kepez State Hospital between 15 March and 01 June and whose diagnosis was confirmed by a positive PCR test were included in the study. The data of the patients were obtained retrospectively from patient files and hospital information management system. Patients were divided into two groups as those with and without cardiac disease. Demographic characteristics, clinical presentations, laboratory tests, radiological imaging results and in-hospital outcomes of the patients were recorded. The data of 30 patients with cardiac disease and 154 patients without cardiac disease were compared. Result(s) 176 of 184 patients were hospitalized. Coronary artery disease was present in 66.7%, atrial fibrillation in 46%, and heart failure in 40% of COVID-19 patients with accompanying cardiac disease. The mean age of patients with cardiac disease was higher than those without cardiac disease (72.5 +/- 15.8 vs 45.4 +/- 15.4, p<0.001). There was no significant difference in presentation symptoms between the two groups. Oxygen saturation at admission was lower and respiratory rate was higher in patients with cardiac disease. Serum creatinine, Hs troponin, D-Dimer, C-reactive protein levels were significantly higher in patients with cardiac disease. When the findings of 174 patients evaluated with thorax computed tomography at the time of admission were compared, no significant difference was found between the groups. The rate of death (20% vs 0% p<0.004), thromboembolic events (13.3% vs 0% p=0.025), acute respiratory distress syndrome (26.7% vs 1.3% p=0.002) and septic shock (33.3% vs 1.3% p<0.001) during hospitalization was higher in patients with cardiac disease. Conclusion(s) Patients with cardiac disease with COVID-19 have higher rates of mortality, thromboembolic events, ARDS and septic shock than those without a history of cardiac disease, and the prognosis of these patients is quite poor.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: Anatolian Journal of Cardiology Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: Anatolian Journal of Cardiology Year: 2021 Document Type: Article