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Transition in the SARS-CoV2 antibody profile after Pfizer/BioNtech vaccine inoculation in persons with and without a history of COVID-19
Journal of the Japanese Association for Infectious Diseases ; 96(2):56-60, 2022.
Article in Japanese | GIM | ID: covidwho-2203543
ABSTRACT

Objective:

We investigated whether there was a difference in the antibody profile after Pfizer/BioNtech vaccination in persons who had already been infected with COVID-19 and those who had not.

Method:

Blood samples were obtained before, after the first dose and after the second dose of Pfizer/BioNtech vaccine inoculation in 4 subjects with a history of COVID-19 infection and 62 subjects without a history of COVID-19 infection after obtaining their informed consent. The differences in the antibody titers were examined between those with and without a prior history of COVID-19.

Result:

As compared with those without a prior history of COVID-19, those with a prior history of COVID-19 showed significantly higher antibody titers after the first inoculation, and the antibody titers were significantly higher than even those after the second inoculation of subjects without a prior history of COVID-19.
Keywords

Full text: Available Collection: Databases of international organizations Database: GIM Type of study: Prognostic study Topics: Vaccines Language: Japanese Journal: Journal of the Japanese Association for Infectious Diseases Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: GIM Type of study: Prognostic study Topics: Vaccines Language: Japanese Journal: Journal of the Japanese Association for Infectious Diseases Year: 2022 Document Type: Article