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Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study.
Sindi, Anees A; Tashkandi, Wail A; Jastaniah, Mohammed W; Bashanfar, Mohammed A; Fakhri, Ahmed F; Alsallum, Fahad S; Alguydi, Hamdan B; Elhazmi, Alyaa; Al-Khatib, Talal A; Alawi, Maha M; Abushoshah, Ibrahim.
  • Sindi AA; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Tashkandi WA; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Jastaniah MW; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Bashanfar MA; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Fakhri AF; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Alsallum FS; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Alguydi HB; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Elhazmi A; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Al-Khatib TA; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Alawi MM; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
  • Abushoshah I; From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Pa
Saudi Med J ; 44(1): 67-73, 2023 Jan.
Article in English | MEDLINE | ID: covidwho-2310992
ABSTRACT

OBJECTIVES:

To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection.

METHODS:

We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM.

RESULTS:

Out of 198 patients included in the study, 86 (43.4%) were diabetic and 112 (56.5%) were non-diabetic. Majority of the patients were males 139 (70.2%) with a mean age of 54.14±14.89 years. In-hospital mortality rate was higher in diabetic patients than in non-diabetic patients (40 vs. 32; p=0.011). The most common comorbidity was hypertension (n=95, 48%) followed by ischemic heart disease (n=35, 17.7%), chronic kidney disease (n=17, 9.6%), and bronchial asthma (n=10, 5.1%).

CONCLUSION:

The risk of SARS-CoV-2 infection is higher among diabetic patients; particularly, those with preexisting co-morbidities or geriatric patients. Diabetic patients are prone to a severe clinical course of COVID-19 and a significantly higher mortality rate.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Saudi Med J Year: 2023 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Saudi Med J Year: 2023 Document Type: Article