CRP/albumin ratio as an age-dependent prognostic factor in patients with COVID-19 pneumonia

ABSTRACT

Purpose: The aim of our study was to determine whether C-reactive protein/albumin is an age-related marker in Covid-19 pneumonia. Materials and Methods: We performed a retrospective research on 296 patients (166 male/130 female) with Covid-19 pneumonia. The participants were divided into two groups as <65 and >= 65 years of age. The need of intensive care unit, pulse steroid requirement and mortality rates were all compared using the The C-reactive protein/albumin ratio. Results: The C-reactive protein/albumin was found to be high in patients over the age of 65 as well as those under the age of 65 who were admitted to the intensive care unit and was found to be significant in demonstrating mortality in patients aged 65 and over. According to univariate analysis, the C-reactive protein/albumin ratio was statistically significant for the risk of intensive care admission in both patients under 65 and over 65 years of age (OR1.515 and OR1.357, respectively). According to multivariate analysis, the CRP/albumin ratio was statistically significant for the risk of intensive care admission, only in patients over the age of 65 (OR1.209). Conclusion: The increased C-reactive protein/albumin levels are thought to be useful in predicting the severity of Covid-19, hospitalisation time, and mortality rates. This variable can be calculated and used to predict the clinical course of Covid-19 pneumonia without regard to age.