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Successful treatment of post–COVID-19 acute disseminated encephalomyelitis with urgent immunotherapy and neurointensive management: a case report
Journal of Neurocritical Care ; 15(2):131-135, 2022.
Article in English | Scopus | ID: covidwho-2204647
ABSTRACT

Background:

Acute disseminated encephalomyelitis (ADEM)-like white matter disease, a rare complication of coronavirus disease 2019 (COVID-19), is a potentially life-threatening neurological disorder. The objective of this study was to report the successful treatment of post–COVID-19 ADEM with urgent immunotherapy and neurointensive management. Case Report A 53-year-old female patient was referred to our hospital with a 2-day history of progressive mental deterioration and was diagnosed with ADEM after COVID-19. The patient's symptoms worsened despite the administration of high-dose steroids, and targeted temperature management was employed to manage brain edema. Additionally, the neurointensivist decided to use intravenous immunoglobulin early for intractable post–COVID-19 ADEM. Her mental status and neuroimaging findings showed rapid im-provement at about 3 months after admission.

Conclusion:

This case highlights that if the patient's symptoms worsen despite high-dose steroid administration in the acute stage, early use of intravenous immunoglobulin is expected to have a positive effect on the prognosis of patients with post–COVID-19 ADEM. © 2022 The Korean Neurocritical Care Society.
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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Case report Topics: Long Covid Language: English Journal: Journal of Neurocritical Care Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Case report Topics: Long Covid Language: English Journal: Journal of Neurocritical Care Year: 2022 Document Type: Article