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CORRELATION OF SARS-COV-2 EXPRESSION IN THE PLACENTA AND THE INCIDENCE OF PREECLAMPSIA.
Sarma, Lumbanraja; Helmy, Effendi Iman; M, Siahaan Andre; E P, Bancin Berry; Deri, Edianto; Edwin Martin, Asroel; Yudha, Sudewo.
  • Sarma L; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • Helmy EI; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • M SA; Neurosurgery Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • E P BB; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • Deri E; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • Edwin Martin A; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
  • Yudha S; Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20136, Indonesia.
Afr J Infect Dis ; 17(1): 45-54, 2023.
Article in English | MEDLINE | ID: covidwho-20238972
ABSTRACT

Background:

The pandemic caused by SARS-CoV-2 also caused infection in some pregnant women. Some reports say this viral infection can show symptoms of preeclampsia. Material and

Methods:

We analyzed 25 pregnant women with SARS-CoV-2 infection with 4 patients presenting with symptoms of preeclampsia. we performed routine blood analysis, renal function, liver function, and IHC examination to see the expression of viral proteins in the placenta.

Results:

we obtained 4 patients with confirmed SARS-CoV-2 infection by RT-PCR. In these 4 cases, none of the cases showed expression of the SARS-CoV-2 viral protein in the placenta, and all 4 mothers were declared dead after treatment, and 2 babies delivered out of these 4 cases died. In one case we had fetal death in pregnancy while in one case prematurity. 2 babies born to mothers with SARS-CoV-2 infection with preeclampsia were born in good condition. There were no babies infected with SARS-CoV-2.

Conclusion:

We conclude that SAR-CoV-2 infection in pregnant women with comorbidities can lead to a poor prognosis for both mother and baby. We cannot yet conclude whether SARS-CoV-2 infection can cause preeclampsia, but SARS-CoV-2 infection can exacerbate preeclampsia symptoms.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Afr J Infect Dis Year: 2023 Document Type: Article Affiliation country: Ajidv17i1.4

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal: Afr J Infect Dis Year: 2023 Document Type: Article Affiliation country: Ajidv17i1.4