Clinical and etiological characteristics of mixed infections in children in the Izhevsk hospital

ABSTRACT

Aim: to study the structure, features of the findings and treatment of mixed infections in children at the present stage. Materials and methods. 85 case histories of children aged 5 months to 17 years and 10 months were examined, the final diagnosis of which included 2 or more infections on the basis of the children's infectious diseases department City Clinical Hospital No. 7 of Izhevsk. Children with acute infectious pathology (acute intestinal infections, acute respiratory infections, herpes infections) are hospitalized in this hospital. Diagnostic methods: polymerase chain reaction, ELISA, bacteriological. Results. Mixed infections are equally common in both boys and girls, while there is a predominance of mixed infections in young children (up to 1 year and from 1 year to 3 years) 62.4%. The structure of infectious morbidity is consistently dominated by acute enteric infection - 83.5% cases and acute respiratory infections - 53.0% cases. The progression of SARS-CoV-2-associated and herpes-associated mixed infections is characterized by a pronounced polymorphism of clinical manifestations. The etiological factor for each nosology was deciphered only in 17.7%;in 43.5% of cases, only one etiological factor was verified in the laboratory;in 38.8% of cases, no etiological factor was confirmed in the laboratory. Copyright © The Author(s) 2022.