Effect of Alkalizing agent variation for Aloe vera Gel Handsanitizer Formulation

ABSTRACT

The aim of the research was to extract of Aloe vera contains active compounds such as alkaloids, phenols, flavonoids and saponins and produce hand sanitizer by Aloe vera extract. Saponin has the ability to inhibit microorganisms growth and has antiseptic properties so that can be used as a formula to produce hand sanitizers. The formulation of Aloe vera extract for handsanitizer is carried out by varying the type of alkalizing agent at a certain pH. The formula consisted of three variations in which each formulation carried out its characteristics in the form of a dispersion test, adhesion test, homogenity test, viscosity test and antiseptic test. Based on the results of the study, it was found that each variation of handsanitizer formulation had a homogeneous structure and the handsanitizer with formula II had a fairly wide dispersive power for gel preparations. Meanwhile, the handsanitizer by Formulation I had the greatest viscosity value, around 837 cps and the longest adhesion value of about 2.44 minutes. Based on the antiseptic test, it was produced that the handsanitizer by formulation I was able to kill more microbial colonies, about 71 microb colonies from the available 107 microbes. It is known that the handsanitizer formulation I is a handsanitizer with a variety of alkalizing agents in the form of triethanolamine (TEA) at pH 5.01.