Stability Indicating RP-HPLC Method for the estimation of Favipiravir in API and Pharmaceutical Dosage Forms (Tablets)
Research Journal of Pharmacy and Technology
; 15(12):5700-5706, 2022.
Article
in English
| EMBASE | ID: covidwho-2207048
ABSTRACT
Favipiravir is an anti-viral agent used for the treatment of a large number of RNA viruses including influenza and was considered for the treatment of COVID-19. A new stability indicating RP-HPLC has been developed for the estimation of Favipiravir and the method was validated. Hypersil BDS C18 column was used for the chromatographic study with a flow rate 1ml/min (Detection wavelength 230nm). The LOD and LOQ were found to be 0.2918mug/mL and 0.9207mug/mL respectively. Linearity was observed over the concentration 1-300mug/mL with linear regression equation, y = 28444x + 21853 (R2 = 09998) and the method is precise, accurate and robust. Stress degradation studies were performed and the method was found to be selective and specific. Copyright © RJPT All right reserved u.
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Research Journal of Pharmacy and Technology
Year:
2022
Document Type:
Article
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