Early Introduction and Community Transmission of SARS-CoV-2 Omicron Variant, New York, New York, USA.
Emerg Infect Dis
; 29(2): 371-380, 2023 02.
Article
in English
| MEDLINE | ID: covidwho-2215191
ABSTRACT
The Omicron variant of SARS-CoV-2 has become dominant in most countries and has raised significant global health concerns. As a global commerce center, New York, New York, USA, constantly faces the risk for multiple variant introductions of SARS-CoV-2. To elucidate the introduction and transmission of the Omicron variant in the city of New York, we created a comprehensive genomic and epidemiologic analysis of 392 Omicron virus specimens collected during November 25-December 11, 2021. We found evidence of 4 independent introductions of Omicron subclades, including the Omicron subclade BA.1.1 with defining substitution of R346K in the spike protein. The continuous genetic divergence within each Omicron subclade revealed their local community transmission and co-circulation in New York, including both household and workplace transmissions supported by epidemiologic evidence. Our study highlights the urgent need for enhanced genomic surveillance and effective response planning for better prevention and management of emerging SARS-CoV-2 variants.
Keywords
COVID-19; Cheng Y; Fiel RH; Gruenstein Y; New York; Omicron; SARS-CoV-2; Suggested citation for this article: Liu D; USA. Emerg Infect Dis. 2023 Feb [date cited]. https://doi.org/10.3201/eid2902.220817; United States; Wang L; Zhou H; co-circulation; community transmission; et al. Early introduction and community transmission of SARS-CoV-2 Omicron variant; household transmission; respiratory infections; subclade multiple introductions; viruses; workplace transmission; zoonoses
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Observational study
/
Prognostic study
Topics:
Variants
Limits:
Humans
Country/Region as subject:
North America
Language:
English
Journal:
Emerg Infect Dis
Journal subject:
Communicable Diseases
Year:
2023
Document Type:
Article
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