Label-free detection of SARS-CoV-2 neutralizing antibodies in human serum by Bloch surface waves on 1D photonic crystal biochips

Occhicone, A.; Sinibaldi, A.; Pileri, T.; Di Matteo, P.; Chiappetta, D.; Munzert, P.; Danz, N.; Sonntag, F.; Allegretti, M.; De Pascale, V.; Mandoj, C.; Conti, L.; Michelotti, F.

Occhicone, A.; Sinibaldi, A.; Pileri, T.; Di Matteo, P.; Chiappetta, D.; Munzert, P.; Danz, N.; Sonntag, F.; Allegretti, M.; De Pascale, V.; Mandoj, C.; Conti, L.; Michelotti, F..

Frontiers in Optics, FiO 2022 ; 2022.

Article in English | Scopus | ID: covidwho-2218880

ABSTRACT

ABSTRACT

We propose a rapid serologic test based on disposable nano-photonic biochips for SARS-CoV-2 related antibodies. The label-free sensograms showed that positive and negative human serum samples were discriminated, enabling real-time and fast label-free detection. © 2022 The Author (s)

Keywords

Antibodies; Chemical detection; Surface waves; 1-D photonic crystal; Disposables; Human serum; Label free; Label-free detection; Nano-photonics; Neutralizing antibodies; Real- time; Serum samples; Biochips

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Collection: Databases of international organizations Database: Scopus Language: English Journal: Frontiers in Optics, FiO 2022 Year: 2022 Document Type: Article

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Collection: Databases of international organizations Database: Scopus Language: English Journal: Frontiers in Optics, FiO 2022 Year: 2022 Document Type: Article