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Nanotechnology-Assisted Biosensors for the Detection of Viral Nucleic Acids: An Overview.
Choi, Hye Kyu; Yoon, Jinho.
  • Choi HK; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.
  • Yoon J; Department of Biomedical-Chemical Engineering, The Catholic University of Korea, Bucheon-si 14662, Gyeonggi-do, Republic of Korea.
Biosensors (Basel) ; 13(2)2023 Jan 30.
Article in English | MEDLINE | ID: covidwho-2225057
ABSTRACT
The accurate and rapid diagnosis of viral diseases has garnered increasing attention in the field of biosensors. The development of highly sensitive, selective, and accessible biosensors is crucial for early disease detection and preventing mortality. However, developing biosensors optimized for viral disease diagnosis has several limitations, including the accurate detection of mutations. For decades, nanotechnology has been applied in numerous biological fields such as biosensors, bioelectronics, and regenerative medicine. Nanotechnology offers a promising strategy to address the current limitations of conventional viral nucleic acid-based biosensors. The implementation of nanotechnologies, such as functional nanomaterials, nanoplatform-fabrication techniques, and surface nanoengineering, to biosensors has not only improved the performance of biosensors but has also expanded the range of sensing targets. Therefore, a deep understanding of the combination of nanotechnologies and biosensors is required to prepare for sanitary emergencies such as the recent COVID-19 pandemic. In this review, we provide interdisciplinary information on nanotechnology-assisted biosensors. First, representative nanotechnologies for biosensors are discussed, after which this review summarizes various nanotechnology-assisted viral nucleic acid biosensors. Therefore, we expect that this review will provide a valuable basis for the development of novel viral nucleic acid biosensors.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Nucleic Acids / Biosensing Techniques / Nanostructures / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Year: 2023 Document Type: Article Affiliation country: Bios13020208

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Nucleic Acids / Biosensing Techniques / Nanostructures / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Year: 2023 Document Type: Article Affiliation country: Bios13020208