Covid-19 Medications and Its Post Effects
International Journal of Applied Pharmaceutics
; 15(1):127.0, 2023.
Article
in English
| EMBASE | ID: covidwho-2227602
ABSTRACT
Till date, over 163 million confirmed cases of COVID-19 and over 3.3 million deaths from COVID-19 have been reported by the World Health Organization (WHO). However, there is still no specific treatment for the disease. Some empirical and supportive medications have been used thus far, including antivirals, antipyretics, antibiotics, and corticosteroids. Corticosteroids are anti-inflammatory and immunosuppressive medications that are used to treat several diseases. These agents can produce undesirable and occasionally severe systemic adverse effects. Although the occurrence and severity of most adverse effects are related to the dose and duration of the corticosteroid therapy, avascular necrosis is not directly associated with this dose and duration, and may occur without osteoporosis. The basis of the use of such corticosteroid drugs in patients suffering from COVID-19 is the immunosuppressant nature of the drugs Corticosteroids are not recommended for routine use in COVID-19 patients by the WHO. But it is widely used by many people for treating this condition. Severe COVID-19 patients are at risk of avascular necrosis due to corticosteroid therapy Avascular necrosis is a progressive and incapacitating condition. The causes of avascular necrosis are categorized into traumatic and non-traumatic. The majority of non-traumatic cases are associated with the use of corticosteroids. Popular corticosteroid drugs and therapies that are being prescribed in patients suffering from COVID-19 are dexamethasone, methylprednisolone and or hydrocortisone with IV (intravenous) and/or oral administration. The use of such high doses of corticosteroids have shown very positive results and have been lifesaving in many cases.
Avascular necrosis; Corticosteroids; covid-19; methylprednisolone; adult; conference abstract; coronavirus disease 2019; corticosteroid therapy; drug megadose; drug therapy; human; intravenous drug administration; oral drug administration; osteoporosis; side effect; World Health Organization; antibiotic agent; antipyretic agent; antivirus agent; corticosteroid; dexamethasone; hydrocortisone; immunosuppressive agent
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Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Experimental Studies
/
Prognostic study
Language:
English
Journal:
International Journal of Applied Pharmaceutics
Year:
2023
Document Type:
Article
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