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Determinants of mortality among hospitalized patients with COVID-19 during first and second waves of the pandemic: A retrospective cohort study from an isolation center in Kano, Nigeria.
Dayyab, Farouq Muhammad; Bashir, Hussain Abdullahi; Sulaiman, Abdulwahab Kabir; Iliyasu, Garba; Hamza, Muhammad; Yakasai, Ahmad Maifada; Nashabaru, Ibrahim; Saidu, Hadiza; Ahmad, Bashir Garba; Dabo, Bashir; Abubakar, Aminu Yusuf; Idris, Ibrahim Musa; Yahaya, Abdulrauf Sani; Ado, Mustapha; Abdurrahman, Ibrahim Sabo; Usman, Hafizu Musa; Bello, Mohammed Kabiru; Jaafar, Jaafar Suleiman; Abdullahi, Anifowose; Alhassan, Abubakar Muhammad; Ahmad, Abdulmalik; Allen, Alika Ehima; Ezekiel, Medu Oghenekevwe; Umar, Muhammad Abdullahi; Abdullahi, Muhammad B; Sulaiman, Sahabi Kabir; Hussaini, Tijjani; Umar, Amina Abdullahi; Tsanyawa, Aminu Ibrahim; Shuaibu, Sabitu Y; Kabo, Nasir Alhassan; Muhammad, Basheer Lawan; Yahaya, Mohammed Nura; Bello, Imam Wada; Rajab, Ashiru; Daiyab, Abdulhakim Muhammad; Kabara, Aminu Faruk; Garko, Muhammad Sule; Habib, Abdulrazaq Garba.
  • Dayyab FM; Department of Medicine, Infectious Disease Hospital, Kano, Kano State, Nigeria.
  • Bashir HA; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Sulaiman AK; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Iliyasu G; Department of Medicine, Muhammad Abdullahi Wase Teaching Hospital, Kano, Kano State, Nigeria.
  • Hamza M; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Yakasai AM; Department of Medicine, Murtala Muhammad Specialist Hospital, Kano, Kano State, Nigeria.
  • Nashabaru I; Infectious Disease Unit, Department of Medicine, College of Health Sciences, Bayero University, Kano, Kano State, Nigeria.
  • Saidu H; Infectious Disease Unit, Department of Medicine, College of Health Sciences, Bayero University, Kano, Kano State, Nigeria.
  • Ahmad BG; Department of Medicine, Yusuf Maitama Sule University, Kano, Kano State, Nigeria.
  • Dabo B; Infectious Disease Unit, Department of Medicine, College of Health Sciences, Bayero University, Kano, Kano State, Nigeria.
  • Abubakar AY; Department of Medicine, Murtala Muhammad Specialist Hospital, Kano, Kano State, Nigeria.
  • Idris IM; Cardiology Unit, Department of Medicine, College of Health Sciences, Bayero University, Kano, Kano State, Nigeria.
  • Yahaya AS; Department of Medicine, Muhammad Abdullahi Wase Teaching Hospital, Kano, Kano State, Nigeria.
  • Ado M; Department of Epidemiology, College of Public Health, University of South Florida, Tampa, Florida, United States of America.
  • Abdurrahman IS; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Usman HM; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Bello MK; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Jaafar JS; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Abdullahi A; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Alhassan AM; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Ahmad A; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Allen AE; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Ezekiel MO; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Umar MA; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Abdullahi MB; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Sulaiman SK; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Hussaini T; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Umar AA; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Tsanyawa AI; Department of Medicine, Kwanar Dawaki Isolation Center, Kano, Kano State, Nigeria.
  • Shuaibu SY; Department of Medicine, Yobe State University Teaching Hospital, Yobe, Yobe State, Nigeria.
  • Kabo NA; Kano State Primary Health Care Management Board, Kano, Kano State, Nigeria.
  • Muhammad BL; Division of Epidemiology and Biostatistics, Department of Community Medicine, Bayero University, Kano, Kano State, Nigeria.
  • Yahaya MN; Kano State Ministry of Health, Kano, Kano State, Nigeria.
  • Bello IW; Kano State Agency for Control of AIDS, Kano, Kano State, Nigeria.
  • Rajab A; Kano State Hospitals Management Board, Kano, Kano State, Nigeria.
  • Daiyab AM; Kano State Ministry of Health, Kano, Kano State, Nigeria.
  • Kabara AF; Kano State Primary Health Care Management Board, Kano, Kano State, Nigeria.
  • Garko MS; Kano State Primary Health Care Management Board, Kano, Kano State, Nigeria.
  • Habib AG; Kano State Ministry of Health, Kano, Kano State, Nigeria.
PLoS One ; 18(2): e0281455, 2023.
Article in English | MEDLINE | ID: covidwho-2229325
ABSTRACT

BACKGROUND:

Coronavirus disease 2019 (COVID-19) has emerged as an important cause of morbidity and mortality worldwide. The aim of this study is to identify the clinical predictors of mortality among patients with COVID-19 pneumonia during first and second waves in a treatment center in northwestern Nigeria.

METHODS:

This was a retrospective cohort study of 195 patients hospitalized with COVID-19 between April 2020 to March 2021 at a designated COVID-19 isolation center in Kano State, Northwest Nigeria. Data were summarized using frequencies and percentages. Unadjusted odds ratios and 95% confidence intervals and p-values were obtained. To determine independent determinants of mortality, we performed a stepwise multivariate logistic regression model.

RESULTS:

Of 195 patients studied, 21(10.77%) patients died. Males comprised 158 (81.03%) of the study population. In the adjusted stepwise logistic regression analysis, age>64 years (OR = 9.476, 95% CI 2.181-41.165), second wave of the pandemic (OR = 49.340, 95% CI6.222-391.247), cardiac complications (OR = 24.984, 95% CI 3.618-172.508), hypertension (OR = 5.831, 95% CI1.413-24.065) and lowest systolic blood pressure while on admission greater than or equal to 90mmHg were independent predictors of mortality (OR = 0.111, 95%CI 0.021-0.581).

CONCLUSION:

Strategies targeted to prioritize needed care to patients with identified factors that predict mortality might improve patient outcome.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2023 Document Type: Article Affiliation country: Journal.pone.0281455

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2023 Document Type: Article Affiliation country: Journal.pone.0281455