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Symptom patterns and life with post-acute COVID-19 in children aged 8-17 years: a mixed-methods study protocol.
Faux-Nightingale, Alice; Burton, Claire; Twohig, Helen; Blagojevic-Bucknall, Milica; Carroll, Will; Chew-Graham, Carolyn A; Dunn, Kate; Gilchrist, Francis; Helliwell, Toby; Lawton, Oliver; Lawton, Sarah; Mallen, Christian; Saunders, Benjamin; van der Windt, Danielle; Welsh, Victoria.
  • Faux-Nightingale A; School of Medicine, Keele University, Keele, Newcastle, UK a.faux-nightingale@keele.ac.uk.
  • Burton C; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Twohig H; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Blagojevic-Bucknall M; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Carroll W; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Chew-Graham CA; Staffordshire Children's Hospital at Royal Stoke, Stoke-on-Trent, United Kingdom.
  • Dunn K; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Gilchrist F; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Helliwell T; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Lawton O; Staffordshire Children's Hospital at Royal Stoke, Stoke-on-Trent, United Kingdom.
  • Lawton S; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Mallen C; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Saunders B; School of Medicine, Keele University, Keele, Newcastle, UK.
  • van der Windt D; School of Medicine, Keele University, Keele, Newcastle, UK.
  • Welsh V; School of Medicine, Keele University, Keele, Newcastle, UK.
BJGP Open ; 7(2)2023 Jun.
Article in English | MEDLINE | ID: covidwho-2229909
ABSTRACT

BACKGROUND:

While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks.

AIM:

To describe longer-term effects of COVID-19 infection in children and young people (CYP) and identify their needs in relation to long-COVID. DESIGN &

SETTING:

This study comprises an observational prospective cohort study and a linked qualitative study, identifying participants aged 8-17 years in the West Midlands of England.

METHOD:

CYP will be invited to complete online questionnaires to monitor incidences and symptoms of COVID-19 over a 12-month period. CYP who have experienced long-term effects of COVID will be invited to interview, and those currently experiencing symptoms will be asked to document their experiences in a diary. Professionals who work with CYP will be invited to explore the impact of long-COVID on the wider experiences of CYP, in a focus group. Descriptive statistics will be used to describe the incidence and rates of resolution of symptoms, and comparisons will be made between exposed and non-exposed groups. Logistic regression models will be used to estimate associations between candidate predictors and the development of long-COVID, and linear regression will be used to estimate associations between candidate predictors. Qualitative data will be analysed thematically using the constant comparison method.

CONCLUSION:

This study will describe features and symptoms of long-COVID and explore the impact of long-COVID within the lives of CYP and their families, to provide better understanding of long-COVID and inform clinical practice.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Language: English Year: 2023 Document Type: Article Affiliation country: Bjgpo.2022.0149

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Language: English Year: 2023 Document Type: Article Affiliation country: Bjgpo.2022.0149