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Bilateral Branch Retinal Vein Occlusion after mRNA-SARS-CoV-2 Booster Dose Vaccination.
Gironi, Matteo; D'Aloisio, Rossella; Verdina, Tommaso; Shkurko, Benjamin; Toto, Lisa; Mastropasqua, Rodolfo.
  • Gironi M; Ophthalmology Clinic, University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena, 41125 Policlinico, Italy.
  • D'Aloisio R; Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, 66100 Chieti, Italy.
  • Verdina T; Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, 66100 Chieti, Italy.
  • Shkurko B; Ophthalmology Clinic, University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena, 41125 Policlinico, Italy.
  • Toto L; Ophthalmology Clinic, Department of Medicine and Surgery, University of Parma, 43121 Parma, Italy.
  • Mastropasqua R; Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D'Annunzio Chieti-Pescara, 66100 Chieti, Italy.
J Clin Med ; 12(4)2023 Feb 07.
Article in English | MEDLINE | ID: covidwho-2230394
ABSTRACT

PURPOSE:

We report a case of a patient with a bilateral branch retinal vein occlusion (BRVO) 24 h after a booster vaccination with the mRNA-1237 vaccine. OBSERVATIONS Fluorescein angiography, performed at three weeks follow-up, showed vascular leakage and blockage, corresponding to hemorrhage areas associated with ischemic areas in the macula and along the arcades involved in the occlusion.

CONCLUSIONS:

The patient was scheduled for urgent injections of intravitreal ranibizumab and laser photocoagulation of the ischemic areas. To the best of our knowledge, this is the first case described of concomitant bilateral RVO after COVID-19 vaccination. The rapid onset of the side effects in a patient with multiple risk factors for thrombotic events suggests that vulnerable microvascular conditions require detailed investigations before administration of a COVID-19 vaccine.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Observational study / Prognostic study Topics: Vaccines Language: English Year: 2023 Document Type: Article Affiliation country: Jcm12041325

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Cohort study / Observational study / Prognostic study Topics: Vaccines Language: English Year: 2023 Document Type: Article Affiliation country: Jcm12041325