Applications of Microfluidics and Nanotechnologies for Point-of-Care Devices

ABSTRACT

In this work, applications of microfluidic devices in the field of biomedical engineering will be described, with special focus on point-of-care tools (POC). These are devices offering rapid and easy-to-read diagnostic assays of various diseases or physiological conditions (COVID-19, allergies, cardiovascular diseases, tumours, pregnancy, etc.) that often can be applied by non-medically trained persons. Microfluidic devices play an important role in the development of POC tools. Recent advances in novel fabrication methods and multi-technology approaches allow to overcome common limitations, such as high cost, complex fluidic controls and pumping systems, or requiring specialized labour equipment and well-trained operators. Hence, these devices can be made available for a broad range of patients that might not have sufficient medical facilities. The influence of point-of-care tools on society, medical practice and early diagnosis will be discussed. Copyright © 2022 The Authors.