Systemic Lupus Erythematosus Risk: The Role of Environmental Factors.
Rheum Dis Clin North Am
; 48(4): 827-843, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-2232614
ABSTRACT
Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease. The etiology of SLE is multifactorial and includes potential environmental triggers, which may occur sequentially (the "multi-hit" hypothesis). This review focuses on SLE risk potentially associated with environmental factors including infections, the microbiome, diet, respirable exposures (eg, crystalline silica, smoking, air pollution), organic pollutants, heavy metals, and ultraviolet radiation.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Environmental Exposure
/
Lupus Erythematosus, Systemic
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Rheum Dis Clin North Am
Journal subject:
Rheumatology
Year:
2022
Document Type:
Article
Affiliation country:
J.rdc.2022.06.005
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