A Study of Infection of SARS-Cov-2 and its Severity among Post Vaccinated Healthcare Workers

ABSTRACT

Background and Objective: Coronaviruses are important human and animal pathogens. At the end of 2019, a novel coronavirus was found as the cause of a bunch of pneumonia cases in Wuhan, China. It rapidly spread in the country of China resulting in an epidemic, followed by a global spread in whole world leading to the pandemic. In February 2020, the World Health Organization coined the term COVID-19, The objectives to carry out this study were 1) To determine incidence of Covid-19 in health care workers after partial or complete vaccination 2) To determine severity of Covid-19 in health care workers after partial or complete vaccination at Designated Covid Hospital and Medical College at North Gujarat, India Methods: A cross sectional retrospective study was carried out at Designated Covid Hospital and Medical College at North Gujarat, India through telephonic and personal interview of health care workers who had received partial or complete vaccination. Key variables of the study were profile of work of health care worker at medical facility, type of vaccine received and how was post vaccination covid-19 infection managed. Result(s) We enrolled total 210 health care workers with mean age of 31.5 years with 69 male and 141 female. Out of 210 health workers, 204(97.14%) were fully vaccinated with two dose of covid-19 vaccines,5(2.38%) were partially vaccinated. Symptomatic infection with Covid-19 occurred in total 12 (5.71%) health care worker >= 14 day after second dose of either vaccine. Only one required hospitalization with oxygen support, rest all are managed with home isolation. Interpretation &Conclusion: One in twenty health care workers got infected with covid-19 after vaccination in present study. Extended research required to get larger data for ascertaining predictors of infection mainly mutation in virus and effect of comorbidity on antibody response after vaccination and severity of disease. Copyright © 2022, Dr Yashwant Research Labs Pvt Ltd. All rights reserved.