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Zebrafish-based platform for emerging bio-contaminants and virus inactivation research.
Patel, Paritosh; Nandi, Aditya; Verma, Suresh K; Kaushik, Neha; Suar, Mrutyunjay; Choi, Eun Ha; Kaushik, Nagendra Kumar.
  • Patel P; Plasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, 01897 Seoul, South Korea.
  • Nandi A; School of Biotechnology, KIIT University, Bhubaneswar 751024, Odisha, India.
  • Verma SK; School of Biotechnology, KIIT University, Bhubaneswar 751024, Odisha, India; Condensed Matter Theory Group, Materials Theory Division, Department of Physics and Astronomy, Uppsala University, Box 516, SE-751 20 Uppsala, Sweden.
  • Kaushik N; Department of Biotechnology, College of Engineering, The University of Suwon, 18323 Hwaseong, Republic of Korea.
  • Suar M; School of Biotechnology, KIIT University, Bhubaneswar 751024, Odisha, India.
  • Choi EH; Plasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, 01897 Seoul, South Korea. Electronic address: ehchoi@kw.ac.kr.
  • Kaushik NK; Plasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, 01897 Seoul, South Korea. Electronic address: kaushik.nagendra@kw.ac.kr.
Sci Total Environ ; 872: 162197, 2023 May 10.
Article in English | MEDLINE | ID: covidwho-2234225
ABSTRACT
Emerging bio-contaminants such as viruses have affected health and environment settings of every country. Viruses are the minuscule entities resulting in severe contagious diseases like SARS, MERS, Ebola, and avian influenza. Recent epidemic like the SARS-CoV-2, the virus has undergone mutations strengthen them and allowing to escape from the remedies. Comprehensive knowledge of viruses is essential for the development of targeted therapeutic and vaccination treatments. Animal models mimicking human biology like non-human primates, rats, mice, and rabbits offer competitive advantage to assess risk of viral infections, chemical toxins, nanoparticles, and microbes. However, their economic maintenance has always been an issue. Furthermore, the redundancy of experimental results due to aforementioned aspects is also in examine. Hence, exploration for the alternative animal models is crucial for risk assessments. The current review examines zebrafish traits and explores the possibilities to monitor emerging bio-contaminants. Additionally, a comprehensive picture of the bio contaminant and virus particle invasion and abatement mechanisms in zebrafish and human cells is presented. Moreover, a zebrafish model to investigate the emerging viruses such as coronaviridae and poxviridae has been suggested.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Influenza in Birds / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Sci Total Environ Year: 2023 Document Type: Article Affiliation country: J.scitotenv.2023.162197

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viruses / Influenza in Birds / COVID-19 Type of study: Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Sci Total Environ Year: 2023 Document Type: Article Affiliation country: J.scitotenv.2023.162197