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COVID-19 Pneumonia Followed by Anti-signal Recognition Particle Antibody-positive Fibrosing Interstitial Lung Disease.
Tateishi, Tomoya; Shimada, Sho; Yamana, Takashi; Iijima, Yuki; Sakakibara, Rie; Mitsumura, Takahiro; Shibata, Sho; Honda, Takayuki; Shirai, Tsuyoshi; Okamoto, Tsukasa; Tamaoka, Meiyo; Sasai, Tsuneo; Miyazaki, Yasunari.
  • Tateishi T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Shimada S; Department of Respiratory Physiology and Sleep Medicine, Tokyo Medical and Dental University, Japan.
  • Yamana T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Iijima Y; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Sakakibara R; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Mitsumura T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Shibata S; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Honda T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Shirai T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Okamoto T; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Tamaoka M; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
  • Sasai T; Department of Pulmonary Immunotherapeutics, Tokyo Medical and Dental University, Japan.
  • Miyazaki Y; Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
Intern Med ; 62(9): 1323-1328, 2023 May 01.
Article in English | MEDLINE | ID: covidwho-2236168
ABSTRACT
Coronavirus disease 2019 (COVID-19) pneumonia is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is frequently accompanied by various sequelae. Interstitial lung diseases (ILDs) are observed in COVID-19 pneumonia patients after recovery, probably due to persistent inflammation in the lungs. We herein report a case of ILD with anti-signal recognition particle antibodies following severe COVID-19 pneumonia. The patient was diagnosed with ILD three months after COVID-19 pneumonia. Although the exact mechanism is unknown, the autoantibody-induced immune response might have been the pulmonary fibrosis trigger in this patient.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Diseases, Interstitial / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2023 Document Type: Article Affiliation country: Internalmedicine.8877-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Diseases, Interstitial / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2023 Document Type: Article Affiliation country: Internalmedicine.8877-21