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Agent-Based Simulation for Infectious Disease Modelling over a Period of Multiple Days, with Application to an Airport Scenario.
Harweg, Thomas; Wagner, Mathias; Weichert, Frank.
  • Harweg T; Department of Computer Science, TU Dortmund University, Otto-Hahn-Str. 16, 44227 Dortmund, North Rhine-Westphalia, Germany.
  • Wagner M; Department of Pathology, University of Saarland Medical School, Homburg Saar Campus, Kirrberger Strasse 100, 66424 Homburg Saar, Saarland, Germany.
  • Weichert F; Department of Computer Science, TU Dortmund University, Otto-Hahn-Str. 16, 44227 Dortmund, North Rhine-Westphalia, Germany.
Int J Environ Res Public Health ; 20(1)2022 12 29.
Article in English | MEDLINE | ID: covidwho-2241350
ABSTRACT
With the COVID-19 pandemic, the role of infectious disease spreading in public places has been brought into focus more than ever. Places that are of particular interest regarding the spread of infectious diseases are international airport terminals, not only for the protection of staff and ground crew members but also to help minimize the risk of the spread of infectious entities such as COVID-19 around the globe. Computational modelling and simulation can help in understanding and predicting the spreading of infectious diseases in any such scenario. In this paper, we propose a model, which combines a simulation of high geometric detail regarding virus spreading with an account of the temporal progress of infection dynamics. We, thus, introduce an agent-based social force model for tracking the spread of infectious diseases by modelling aerosol traces and concentration of virus load in the air. We complement this agent-based model to have consistency over a period of several days. We then apply this model to investigate simulations in a realistic airport setting with multiple virus variants of varying contagiousness. According to our experiments, a virus variant has to be at least twelve times more contagious than the respective control to result in a level of infection of more than 30%. Combinations of agent-based models with temporal components can be valuable tools in an attempt to assess the risk of infection attributable to a particular virus and its variants.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / COVID-19 Type of study: Observational study / Prognostic study Topics: Variants Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Ijerph20010545

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Diseases / COVID-19 Type of study: Observational study / Prognostic study Topics: Variants Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Ijerph20010545