A tale of two waves: Characteristics and outcomes of COVID-19 admissions during the omicron-driven 4th wave in Cape Town, South Africa and implications for the future.
IJID Reg
; 2022 Nov 24.
Article
in English
| MEDLINE | ID: covidwho-2243459
ABSTRACT
Objectives:
We aimed to describe the pattern of admissions during the fourth wave of COVID-19 to inform future public health policies.Methods:
This was a retrospective descriptive study of an early cohort of all adult patients admitted to a tertiary hospital in Cape Town, South Africa, with SARS-CoV-2 infection at the start of the country's fourth wave. This was compared to an early cohort from the first wave at the same institution.Results:
We included 121 SARS-CoV-2 positive admissions from the fourth wave. Thirty-one (25.6%) patients had COVID-19 pneumonia, while 90 (74.4%) had incidental SARS-CoV-2 infection. In the first wave all 116 patients had COVID-19 pneumonia. Thirty-two (26.4%) patients self-reported complete or partial COVID-19 vaccination, of whom 12 (37.5%) were admitted with COVID-19 pneumonia. Compared to the first wave, there were fewer intensive or high care admissions (18/121 [14.9%] vs 42/116 [36.2%], p<0.001) and lower mortality (12/121 [9.9%] vs 31/116 [26.7%], p=0.001).Conclusion:
Admissions to the COVID-19 wards during the fourth wave primarily included patients with incidental SARS-CoV-2 infection. There was a reduction in the need for critical care and in-hospital mortality. This changing epidemiology of COVID-19 admissions may be attributed to a combination of natural and/or vaccination-acquired immunity.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Topics:
Vaccines
/
Variants
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
J.ijregi.2022.11.008
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