Outcomes of elective cancer surgery in COVID-19 survivors: An observational study
Journal of Surgical Oncology
; 127(1):43040.0, 2023.
Article
in English
| Scopus | ID: covidwho-2244506
ABSTRACT
Background and Objectives:
Guidelines recommend deferral of elective surgery after COVID-19. Delays in cancer surgeries may affect outcomes. We examined perioperative outcomes of elective cancer surgery in COVID-19 survivors. The primary objective was 30-day all-cause postoperative mortality. The secondary objectives were 30-day morbidity, and its association with COVID-19 severity, and duration between COVID-19 and surgery.Methods:
We collected data on age, gender, comorbidities, COVID-19 severity, preoperative investigations, surgery performed, and intra and postoperative outcomes in COVID-19 survivors who underwent elective cancer surgery at a tertiary-referral cancer center.Results:
Three hundred and forty-eight COVID-19 survivors presented for elective cancer surgery. Of these, 332/348 (95%) patients had mild COVID-19 and 311 (89%) patients underwent surgery. Among patients with repeat investigations, computerized tomography scan of the thorax showed the maximum new abnormalities (30/157, 19%). The 30-day all-cause mortality was 0.03% (1/311) and 30-day morbidity was 17% (54/311). On multivariable analysis, moderate versus mild COVID-19 (odds ratio [OR] 1.95;95% confidence interval [CI] 0.52–7.30;p = 0.32) and surgery within 7 weeks of COVID-19 (OR 0.61;95% CI 0.33–1.11;p = 0.10) were not associated with postoperative morbidity.Conclusions:
In patients who recover from mild to moderate COVID-19, elective cancer surgery can proceed safely even within 7 weeks. Additional preoperative tests may not be indicated in these patients. © 2022 Wiley Periodicals LLC.
amino terminal pro brain natriuretic peptide; C reactive protein; D dimer; fibrinogen; troponin I; adult; age; Article; cancer surgery; cancer therapy; comorbidity; computer assisted tomography; controlled study; coronavirus disease 2019; echocardiography; elective surgery; electrocardiography; fatality; female; gender; hospital discharge; human; intensive care unit; major clinical study; male; middle aged; morbidity; mortality rate; observational study; outcome assessment; peroperative complication; postoperative complication; preoperative evaluation; six minute walk test; surgical mortality; survivor; tertiary care center; thorax radiography; cancer; COVID-19; operative; postacute COVID-19 syndrome; postoperative complications; surgical procedures
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Journal of Surgical Oncology
Year:
2023
Document Type:
Article
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