Natural Compounds as Potential Anti-COVID Agents
Anti-Infective Agents
; 21(1):41334.0, 2023.
Article
in English
| Scopus | ID: covidwho-2244512
ABSTRACT
Background:
Since December 2019, COVID-19 has become a new health crisis in the world and has been declared a public health emergency of international concern by WHO. In search of anti-COVID treatment regimen, we applied molecular docking approach in order to identify the natural compounds that may have potential for anti-COVID treatment with specific target and selective inhibitory mechanism. Our goal is to identify the potential anti-COVID compounds based on virtual screening of the protein of spike glycoprotein as virtual inhibition target.Methods:
Molecular docking was carried out by using Molergo Virtual Docker. 35 compounds from different plant sources were selected and docked in the enzyme pocket.Results:
The docking result revealed that some of the compounds exhibited good potency against the virus and can be used further for developing new drug regimen.Conclusion:
The compounds of natural origin could be a good target and can be used as lead compounds for the treatment of this dreadful disease. © 2023 Bentham Science Publishers.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Anti-Infective Agents
Year:
2023
Document Type:
Article
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