Diabetes mellitus: Lessons from COVID-19 for monkeypox infection.
Prim Care Diabetes
; 17(2): 113-118, 2023 04.
Article
in English
| MEDLINE | ID: covidwho-2244737
ABSTRACT
BACKGROUND AND AIMS:
Type 2 Diabetes Mellitus is known to be linked to malfunctioning antiviral defense; however, its association with the severity of monkeypox is poorly understood. In this review, we discuss key immunological mechanisms in the antiviral response affected by poor glucose control that could impact the susceptibility and severity of monkeypox infection, leading to a heightened emphasis on the use of the available antidiabetic drugs.METHODS:
We searched PubMed and Google scholar for articles published from January 1985 to August 2022. No criteria for publication data were set, and all articles in English were included.RESULTS:
Currently, there are no studies about the risk or consequences of monkeypox infection in the diabetic population. A high incidence of diabetes is reported in countries such as China, India, Pakistan, EUA, Indonesia, Brazil, Mexico, Bangladesh, Japan, and Egypt, where unfortunately imported cases of monkeypox have been reported and the infection continues to spread.CONCLUSIONS:
High incidence of diabetes together with the cessation of smallpox vaccination has left large numbers of the human population unprotected against monkeypox. The best option for the population remains confined to the prevention of infection as well as the use of hypoglycemic agents that have also been shown to improve immune mechanisms associated with viral protection.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Monkeypox
/
Diabetes Mellitus, Type 2
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Reviews
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Prim Care Diabetes
Journal subject:
Endocrinology
Year:
2023
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS