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Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians.
Setiabudi, Djatnika; Sukur, Ria Resti; Nugraha, Harry Galuh; Nataprawira, Heda Melinda.
  • Setiabudi D; Department of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
  • Sukur RR; Department of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
  • Nugraha HG; Department of Radiology, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, IndonesiaI.
  • Nataprawira HM; Department of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
IDCases ; 32: e01724, 2023.
Article in English | MEDLINE | ID: covidwho-2245067
ABSTRACT
Cytomegalovirus (CMV) pneumonitis infections might present mild or severe illnesses and need sophisticated diagnostic tools, so it remains a diagnostic challenge. We reported five infants diagnosed with CMV pneumonitis who were initially and undiagnosed by the pediatrician in secondary private or public health hospitals with no improvement with standard and escalation of antibiotics treatment for bronchopneumonia as the initial diagnoses. As all cases occurred during the COVID-19 pandemic, they proved negative COVID-19 identified by polymerase chain reaction (PCR) SARS-CoV-2. We diagnosed acquired perinatal pneumonitis CMV in all claims based on clinical criteria, imaging studies, CMV serology, and PCR-CMV urinary tests as diagnostic tools. They showed clinical improvement after two weeks of valganciclovir therapy. Other organs' involvement was considered to be evaluated, including brain-evoked response audiometry (BERA) and eye examination. The physician should consider the possibility of CMV pneumonitis, who did not respond to standard and escalation of antibiotics treatment after initial diagnoses of bronchopneumonia.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Diagnostic study / Experimental Studies / Prognostic study Language: English Journal: IDCases Year: 2023 Document Type: Article Affiliation country: J.idcr.2023.e01724

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Diagnostic study / Experimental Studies / Prognostic study Language: English Journal: IDCases Year: 2023 Document Type: Article Affiliation country: J.idcr.2023.e01724