A comprehensive review on graphene FET bio-sensors and their emerging application in DNA/RNA sensing & rapid Covid-19 detection

ABSTRACT

In recent years, the significance of biosensors has increased rapidly due to the growing demand for rapid detection of various biomarkers with high selectivity and sensitivity. Among different biosensors, Graphene Field Effect Transistor (Gr-FET) based biosensors has emerged as a promising device and exhibited wide range of application prospects. Gr-FET biosensors are ideal for ultra-sensitive immunological diagnosis applications as it can sense surrounding changes on their surface with low noise. Recently Gr-FET based biosensors have gained profound research interest among scientific community because of its ability in detection of SARS-CoV-2 (corona virus-2). This review article highlights the sensing performance and characteristics of different Gr-FET biosensors like DNA sensor, RNA sensor, glucose sensor, lactose sensor, protein sensor, pH sensor, various bacteria and virus detecting sensors etc.This article also critically reviews the recent progress in Gr-FET based SARS- CoV-2 covid-19 virus detection bio-sensors. © 2022 Elsevier Ltd