Encephalopathy after COVID-19 vaccination during treatment with nivolumab: A case report.
Clin Neurol Neurosurg
; 226: 107632, 2023 03.
Article
in English
| MEDLINE | ID: covidwho-2245607
ABSTRACT
Vaccination is useful for the prevention of COVID-19 and is recommended for everyone, especially people with a weakened immune system. However, various neurological complications have been reported following vaccination. Here, we report the case of a 25 years-old, Japanese man, who presented with acute encephalopathy two days after the second dose of the COVID-19 vaccine. He had been treated with nivolumab, a medication used to treat cancer. He had a high fever and was confused upon admission, and the antibody test was positive for anti-myelin oligodendrocyte glycoproteins. Abnormal signal intensity at the splenium corporis callosi was observed on diffusion-weighted imaging of the brain. We diagnosed him with autoimmune encephalitis and initiated intravenous methylprednisolone, after which, the patient's symptoms rapidly subsided.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Brain Diseases
/
COVID-19
Type of study:
Case report
Topics:
Vaccines
Limits:
Humans
/
Male
Language:
English
Journal:
Clin Neurol Neurosurg
Year:
2023
Document Type:
Article
Affiliation country:
J.clineuro.2023.107632
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