Updated analysis to reject the laboratory-engineering hypothesis of SARS-CoV-2.
Environ Res
; 224: 115481, 2023 05 01.
Article
in English
| MEDLINE | ID: covidwho-2246409
ABSTRACT
A clear understanding of the origin of SARS-CoV-2 is important for future pandemic preparedness. Here, I provided an updated analysis of the type IIS endonuclease maps in genomes of alphacoronavirus, betacoronavirus, and SARS-CoV-2. Scenarios to engineer SARS-CoV-2 in the laboratory and the associated workload was also discussed. The analysis clearly shows that the endonuclease fingerprint does not indicate a synthetic origin of SARS-CoV-2 and engineering a SARS-CoV-2 virus in the laboratory is extremely challenging both scientifically and financially. On the contrary, current scientific evidence does support the animal origin of SARS-CoV-2.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Alphacoronavirus
/
COVID-19
Limits:
Animals
Language:
English
Journal:
Environ Res
Year:
2023
Document Type:
Article
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