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Impact of vaccination on the dynamics of COVID-19: A mathematical study using fractional derivatives
International Journal of Biomathematics ; : 1, 2023.
Article in English | Academic Search Complete | ID: covidwho-2251095
ABSTRACT
Arrival of a new disease marks a yearlong destruction of human lives and economy in general, and if the disease turns out to be a pandemic the loss is frightening. COVID-19 is one such pandemic that has claimed millions of lives till date. There is a suffering throughout the world due to various factors associated with the pandemic, be it loss of livelihoods because of sudden shutdown of companies and lockdown, or loss of lives due to lack of medical aid and inadequate vaccination supplies. In this study, we develop a six-compartmental epidemiological model incorporating vaccination. The motivation behind the study is to analyze the significance of higher vaccination efficacy and higher rate of population getting vaccinated in controlling the rise in infectives and thereby the untimely demise of various individuals. The work begins with an ordinary differential equation model followed by stability analysis of the same, after which a fractional-order derivative model of the same is formulated and the existence of uniformly stable solution for the system is proved. In addition to this, we present the stability of the equilibria in general for the fractional model framed. The sensitivity analysis of the basic reproduction number along with its correlation with various parameters is presented. In addition to this, sensitivity of certain state variables in the fractional model with respect to different fractional orders as well with respect to different infection rate is exhibited in this work. Factors related to lockdown and usage of face shields are incorporated in the entire study, and importance of these is highlighted in the study as well. The major takeaway from the study is that mere vaccination will not suffice in eradication of the virus. The vaccine efficacy plays a major role along with other intervention included in the model. The numerical simulations are carried out in MATLAB software using ode45 and fde12. [ FROM AUTHOR] Copyright of International Journal of Biomathematics is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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Full text: Available Collection: Databases of international organizations Database: Academic Search Complete Type of study: Experimental Studies Topics: Vaccines Language: English Journal: International Journal of Biomathematics Year: 2023 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Academic Search Complete Type of study: Experimental Studies Topics: Vaccines Language: English Journal: International Journal of Biomathematics Year: 2023 Document Type: Article