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Covid-19 rapid test by combining a Random Forest-based web system and blood tests.
Barbosa, Valter Augusto de Freitas; Gomes, Juliana Carneiro; de Santana, Maíra Araújo; de Lima, Clarisse Lins; Calado, Raquel Bezerra; Bertoldo Júnior, Cláudio Roberto; Albuquerque, Jeniffer Emidio de Almeida; de Souza, Rodrigo Gomes; de Araújo, Ricardo Juarez Escorel; Mattos Júnior, Luiz Alberto Reis; de Souza, Ricardo Emmanuel; Dos Santos, Wellington Pinheiro.
  • Barbosa VAF; Federal University of Pernambuco, Recife, Brazil.
  • Gomes JC; Polytechnique School, University of Pernambuco, Recife, Brazil.
  • de Santana MA; Polytechnique School, University of Pernambuco, Recife, Brazil.
  • de Lima CL; Polytechnique School, University of Pernambuco, Recife, Brazil.
  • Calado RB; Federal University of Pernambuco, Recife, Brazil.
  • Bertoldo Júnior CR; Federal University of Pernambuco, Recife, Brazil.
  • Albuquerque JEA; Federal University of Pernambuco, Recife, Brazil.
  • de Souza RG; Federal University of Pernambuco, Recife, Brazil.
  • de Araújo RJE; Federal University of Pernambuco, Recife, Brazil.
  • Mattos Júnior LAR; Federal University of Pernambuco, Recife, Brazil.
  • de Souza RE; Federal University of Pernambuco, Recife, Brazil.
  • Dos Santos WP; Federal University of Pernambuco, Recife, Brazil.
J Biomol Struct Dyn ; : 1-20, 2021 Aug 31.
Article in English | MEDLINE | ID: covidwho-2251243
ABSTRACT
The disease caused by the new type of coronavirus, Covid-19, has posed major public health challenges for many countries. With its rapid spread, since the beginning of the outbreak in December 2019, the disease transmitted by SARS-CoV-2 has already caused over 2 million deaths to date. In this work, we propose a web solution, called Heg.IA, to optimize the diagnosis of Covid-19 through the use of artificial intelligence. Our system aims to support decision-making regarding to diagnosis of Covid-19 and to the indication of hospitalization on regular ward, semi-ICU or ICU based on decision a Random Forest architecture with 90 trees. The main idea is that healthcare professionals can insert 41 hematological parameters from common blood tests and arterial gasometry into the system. Then, Heg.IA will provide a diagnostic report. The system reached good results for both Covid-19 diagnosis and to recommend hospitalization. For the first scenario we found average results of accuracy of 92.891%±0.851, kappa index of 0.858 ± 0.017, sensitivity of 0.936 ± 0.011, precision of 0.923 ± 0.011, specificity of 0.921 ± 0.012 and area under ROC of 0.984 ± 0.003. As for the indication of hospitalization, we achieved excellent performance of accuracies above 99% and more than 0.99 for the other metrics in all situations. By using a computationally simple method, based on the classical decision trees, we were able to achieve high diagnosis performance. Heg.IA system may be a way to overcome the testing unavailability in the context of Covid-19.Communicated by Ramaswamy H. Sarma.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Randomized controlled trials Language: English Journal: J Biomol Struct Dyn Year: 2021 Document Type: Article Affiliation country: 07391102.2021.1966509

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Randomized controlled trials Language: English Journal: J Biomol Struct Dyn Year: 2021 Document Type: Article Affiliation country: 07391102.2021.1966509