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Bariatric Surgery and COVID-19 Outcomes: A Systematic Review and Meta-analysis
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery ; 2023.
Article in English | EuropePMC | ID: covidwho-2253503
ABSTRACT
Background Obesity and its associated complications have a negative impact on human health. Metabolic and bariatric surgery (MBS) ameliorates a series of clinical manifestations associated with obesity. However, the overall efficacy of MBS on COVID-19 outcomes remains unclear. Objectives The objective of this article is to analyse the relationship between MBS and COVID-19 outcomes. Settings A meta-analysis. Methods The PubMed, Embase, Web of Science and Cochrane Library databases were searched to retrieve the related articles from inception to December 2022. All original articles reporting MBS-confirmed SARS-CoV-2 infection were included. Outcomes including hospital admission, mortality, intensive care unit (ICU) admission, mechanical ventilation utilization, haemodialysis during admission and hospital stay were selected. Meta-analysis with fixed or random-effect models were used and reported in terms of odds ratios (ORs) or weighted mean differences (WMDs) along with their 95% confidence intervals (CIs). Heterogeneity was assessed with the I2 test. Study quality was assessed using the Newcastle–Ottawa scale (NOS). Results A total of ten clinical trials involving the investigation of 150848 patients undergoing MBS interventions were included. Patients who underwent MBS had a lower risk of hospital admission (OR 0.47, 95% CI 0.34-0.66, I2 = 0%), mortality (OR 0.43, 95% CI 0.28-0.65, I2 = 63.6%), ICU admission (OR 0.41, 95% CI 0.21-0.77, I2 = 0%), and mechanical ventilation (OR 0.51, 95% CI 0.35-0.75, I2 = 56.2%) than those who did not undergo surgery, but MBS did not affect haemodialysis risk or COVID-19 infection rate. In addition, the length of hospital stay for COVID-19 patients after MBS was significantly reduced (WMD -1.81, 95% CI -3.11-0.52, I2 = 82.7%). Conclusion Our findings indicate that MBS is shown to improve COVID-19 outcomes, including hospital admission, mortality, ICU admission, mechanical ventilation, and hospital stay. Obese patients who have undergone MBS infected with COVID-19 will have better clinical outcomes than those without MBS.
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Collection: Databases of international organizations Database: EuropePMC Type of study: Reviews / Systematic review/Meta Analysis Language: English Journal: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Year: 2023 Document Type: Article

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Collection: Databases of international organizations Database: EuropePMC Type of study: Reviews / Systematic review/Meta Analysis Language: English Journal: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Year: 2023 Document Type: Article