Heart Transplantation from COVID-19-Positive Donors: A Word of Caution.
Transplant Proc
; 55(3): 533-539, 2023 Apr.
Article
in English
| MEDLINE | ID: covidwho-2254005
ABSTRACT
BACKGROUND:
During the COVID-19 pandemic, efforts to maintain solid-organ transplantation have continued, including the use of SARS-CoV-2-positive heart donors.METHODS:
We present our institution's initial experience with SARS-CoV-2-positive heart donors. All donors met our institution's Transplant Center criteria, including a negative bronchoalveolar lavage polymerase chain reaction result. All but 1 patient received postexposure prophylaxis with anti-spike monoclonal antibody therapy, remdesivir, or both.RESULTS:
A total of 6 patients received a heart transplant from a SARS-CoV-2-positive donor. One heart transplant was complicated by catastrophic secondary graft dysfunction requiring venoarterial extracorporeal membrane oxygenation and retransplant. The remaining 5 patients did well postoperatively and were discharged from the hospital. None of the patients had evidence of COVID-19 infection after surgery.CONCLUSION:
Heart transplants from SARS-CoV-2 polymerase chain reaction-positive donors are feasible and safe with adequate screening and postexposure prophylaxis.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Heart Transplantation
/
COVID-19
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Transplant Proc
Year:
2023
Document Type:
Article
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