A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications
Qeios
; 2020.
Article
in English
| EuropePMC | ID: covidwho-2254334
ABSTRACT
SARS-CoV-2 epidemics raises a considerable issue of public health at the planetary scale. There is a pressing urgency to find treatments based upon currently available scientific knowledge. Therefore, we tentatively propose a hypothesis which hopefully might ultimately help saving lives. Based on the current scientific literature and on new epidemiological data which reveal that current smoking status appears to be a protective factor against the infection by SARS-CoV-2 [1], we hypothesize that the nicotinic acetylcholine receptor (nAChR) plays a key role in the pathophysiology of Covid-19 infection and might represent a target for the prevention and control of Covid-19 infection.
Full text:
Available
Collection:
Databases of international organizations
Database:
EuropePMC
Language:
English
Journal:
Qeios
Year:
2020
Document Type:
Article
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