Detection of antibodies to SARS-CoV-2 after vaccination in seminal plasma and their association to sperm parameters
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
; 2023.
Article
in English
| EuropePMC | ID: covidwho-2254862
ABSTRACT
There is public concern that COVID-19 vaccination and SARS-CoV-2 antibodies negatively affect male fertility. However, evidence for the presence of SARS-CoV-2 antibodies in seminal plasma is lacking. We examined whether antibodies were detectable in seminal plasma after COVID-19 vaccination in 86 men via a direct antibody measurement and by quantification of their neutralizing activity. The results show the presence of SARS-CoV-2 antibodies in seminal plasma with a strong correlation to the serum antibodies, increasing with the number of vaccinations. Further, the antibody titers are correlating with the neutralization activity. The SARS-CoV-2 vaccination parameters showed no association with markers of sperm quality. Conclusively, this study indicates substantial levels of antibodies in seminal plasma after COVID-19 vaccination that correlate with serum antibody titers, but do not associate with sperm quality. Graphical Image, graphical
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Collection:
Databases of international organizations
Database:
EuropePMC
Topics:
Vaccines
Language:
English
Journal:
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Year:
2023
Document Type:
Article
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