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Surveillance for Multisystem Inflammatory Syndrome in US Children Aged 5-11 Years Who Received Pfizer-BioNTech COVID-19 Vaccine, November 2021 through March 2022.
Cortese, Margaret M; Taylor, Allan W; Akinbami, Lara J; Thames-Allen, Andrea; Yousaf, Anna R; Campbell, Angela P; Maloney, Susan A; Harrington, Theresa A; Anyalechi, E Gloria; Munshi, Datta; Kamidani, Satoshi; Curtis, C Robinette; McCormick, David W; Staat, Mary A; Edwards, Kathryn M; Creech, C Buddy; Museru, Oidda; Marquez, Paige; Thompson, Deborah; Su, John R; Schlaudecker, Elizabeth P; Broder, Karen R.
  • Cortese MM; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Taylor AW; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Akinbami LJ; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Thames-Allen A; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Yousaf AR; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Campbell AP; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Maloney SA; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Harrington TA; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Anyalechi EG; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Munshi D; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Kamidani S; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Curtis CR; Center for Childhood Infections and Vaccines, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
  • McCormick DW; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Staat MA; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Edwards KM; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Creech CB; Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Museru O; Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Marquez P; Vanderbilt University Vaccine Research, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Thompson D; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Su JR; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Schlaudecker EP; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Broder KR; CDC COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Infect Dis ; 228(2): 143-148, 2023 Jul 14.
Article in English | MEDLINE | ID: covidwho-2255658
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection; in the United States, reporting of MIS-C after coronavirus disease 2019 (COVID-19) vaccination is required for vaccine safety monitoring. Pfizer-BioNTech COVID-19 vaccine was authorized for children aged 5-11 years on 29 October 2021. Covering a period when approximately 7 million children received vaccine, surveillance for MIS-C ≤ 90 days postvaccination using passive systems identified 58 children with MIS-C and laboratory evidence of past/recent SARS-CoV-2 infection, and 4 without evidence. During a period with extensive SARS-CoV-2 circulation, MIS-C illness in children after COVID-19 vaccination who lacked evidence of SARS-CoV-2 infection was rare (<1 per million vaccinated children).
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Screening_studies Topics: Vaccines Limits: Child / Humans Language: English Journal: J Infect Dis Year: 2023 Document Type: Article Affiliation country: Infdis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Screening_studies Topics: Vaccines Limits: Child / Humans Language: English Journal: J Infect Dis Year: 2023 Document Type: Article Affiliation country: Infdis