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Advances in Electrochemical Biosensors Based on Nanomaterials for Protein Biomarker Detection in Saliva.
Dong, Tao; Matos Pires, Nuno Miguel; Yang, Zhaochu; Jiang, Zhuangde.
  • Dong T; Department of Microsystems- IMS, Faculty of Technology, Natural Sciences and Maritime Sciences, University of South-Eastern Norway-USN, P.O. Box 235, Kongsberg, 3603, Norway.
  • Matos Pires NM; Chongqing Key Laboratory of Micro-Nano Systems and Intelligent Transduction, Collaborative Innovation Center on Micro-Nano Transduction and Intelligent Eco-Internet of Things, Chongqing Key Laboratory of Colleges and Universities on Micro-Nano Systems Technology and Smart Transducing, National Resea
  • Yang Z; Chongqing Key Laboratory of Micro-Nano Systems and Intelligent Transduction, Collaborative Innovation Center on Micro-Nano Transduction and Intelligent Eco-Internet of Things, Chongqing Key Laboratory of Colleges and Universities on Micro-Nano Systems Technology and Smart Transducing, National Resea
  • Jiang Z; Chongqing Key Laboratory of Micro-Nano Systems and Intelligent Transduction, Collaborative Innovation Center on Micro-Nano Transduction and Intelligent Eco-Internet of Things, Chongqing Key Laboratory of Colleges and Universities on Micro-Nano Systems Technology and Smart Transducing, National Resea
Adv Sci (Weinh) ; 10(6): e2205429, 2023 02.
Article in English | MEDLINE | ID: covidwho-2257470
ABSTRACT
The focus on precise medicine enhances the need for timely diagnosis and frequent monitoring of chronic diseases. Moreover, the recent pandemic of severe acute respiratory syndrome coronavirus 2 poses a great demand for rapid detection and surveillance of viral infections. The detection of protein biomarkers and antigens in the saliva allows rapid identification of diseases or disease changes in scenarios where and when the test response at the point of care is mandated. While traditional methods of protein testing fail to provide the desired fast results, electrochemical biosensors based on nanomaterials hold perfect characteristics for the detection of biomarkers in point-of-care settings. The recent advances in electrochemical sensors for salivary protein detection are critically reviewed in this work, with emphasis on the role of nanomaterials to boost the biosensor analytical performance and increase the reliability of the test in human saliva samples. Furthermore, this work identifies the critical factors for further modernization of the nanomaterial-based electrochemical sensors, envisaging the development and implementation of next-generation sample-in-answer-out systems.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biosensing Techniques / Nanostructures / COVID-19 Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Adv Sci (Weinh) Year: 2023 Document Type: Article Affiliation country: Advs.202205429

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biosensing Techniques / Nanostructures / COVID-19 Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Adv Sci (Weinh) Year: 2023 Document Type: Article Affiliation country: Advs.202205429