Headache as a COVID-19 onset symptom or Post-COVID symptom according to the SARS-CoV-2 Variant.
Expert Rev Neurother
; 23(2): 179-186, 2023 02.
Article
in English
| MEDLINE | ID: covidwho-2259033
ABSTRACT
INTRODUCTION:
COVID19 associated headaches are highly common and there is currently an unmet need to better understand their association with SARSCoV2 variants. Headaches are a prevalent symptom in the acute phase of COVID19 and are associated with a better prognosis and better immune response. They are also a relevant post-COVID symptom. AREAS COVERED This article analyses the differences in the prevalence of headache as an onset symptom and in post-COVID headache among the different SARS-CoV-2 variants the historical strain, Alpha, Delta and Omicron. The different pathophysiological mechanisms by which SARS-CoV-2 infection may cause headache are also discussed. EXPERT OPINION The presence of headache at the acute phase is a risk factor for post-COVID headache, whereas a history of primary headache does not appear to be associated with post-COVID headache. The prevalence of headache as an onset symptom appears to be variable for the different SARS-CoV-2 variants, but current data are inconclusive. However, the current evidence also suggests that headache represents a prevalent symptom in the acute and post-infection COVID-19 phase, regardless of SARS-CoV-2 variant.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Post-Acute COVID-19 Syndrome
/
Headache
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
/
Variants
Limits:
Animals
/
Humans
Language:
English
Journal:
Expert Rev Neurother
Journal subject:
Neurology
/
Therapeutics
Year:
2023
Document Type:
Article
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