Performance of the PanbioTM COVID-19 Ag rapid test in a health care setting in Ouagadougou, Burkina Faso
African Journal of Microbiology Research
; 16(11):334-342, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2260281
ABSTRACT
This study aimed to evaluate the performance of the PanbioTM Covid-19 Ag Rapid Test (Abbott) in a medical center in Ouagadougou. The PanbioTM COVID-19 Ag test was evaluated from January 26 to March 31, 2021 in symptomatic and asymptomatic patients in the medical Centre of Kossodo. A total of 268 individuals were tested by both SARS-CoV-2 RT-PCR, and antigen RDT. Of these 268 individuals, 52 were positive and 216 were negative for COVID-19 RT-PCR. The performance parameters of the test and its Kappa agreement with the RT-PCR were calculated according to the presence or absence of symptoms in the patients on one hand, and according to the time onset of symptoms on the other hand. The sensitivity of the PanbioTM COVID-19 Ag Rapid Test ranged from 29.63% (95% CI 13.75 to 50.18) among COVID-19 asymptomatic patients, to 87.5% (95% CI 52.91 to97.76) among symptomatic patients with symptom onset time of 1-5 days. Similarly, the PanbioTM COVID-19 Ag Rapid Test specificity was 97.3% (95% CI 90.58 to 99.67) and 96.4% (95% CI 91.81 to 98.82) in symptomatic and asymptomatic RT PCR negative patients. The PanbioTM COVID-19 Ag Rapid Test shows good performance in detecting COVID-19 cases in patients with a symptom onset time of less than seven (7) days. This performance is even better when the symptom onset is reduced to five (5) days. The results show that the antigen RDT is not suitable for COVID-19 detection among asymptomatic patients.
Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210], Diagnosis of Human Disease [VV720], Human Immunology and Allergology [VV055], Techniques and Methodology [ZZ900], Health Services [UU350], human diseases, coronavirus disease 2019, viral diseases, pandemics, public health, antigens, antigen testing, rapid methods, serological surveys, seroprevalence, disease prevention, epidemiology, diagnosis, diagnostic techniques, immunological techniques, techniques, analytical methods, health care, reverse transcriptase PCR, asymptomatic infections, symptoms, man, Severe acute respiratory syndrome coronavirus 2, Burkina Faso, Homo, Hominidae, primates, mammals, vertebrates, Chordata, animals, eukaryotes, Severe acute respiratory syndrome-related coronavirus, Betacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, ACP Countries, Francophone Africa, Africa, Least Developed Countries, low Human Development Index countries, low income countries, West Africa, Africa South of Sahara, SARS-CoV-2, viral infections, antigenicity, immunogens, antigen detection, antigen tests, seroepidemiology, serological techniques, analytical techniques, subsaharan Africa, Bourkina Fasso, reverse transcriptase polymerase chain reaction, RT-PCR
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
African Journal of Microbiology Research
Year:
2022
Document Type:
Article
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