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Impact of COVID-19 on Outcomes of Patients Hospitalized With STEMI: A Nationwide Propensity-matched Analysis.
Goel, Akshay; Malik, Aaqib H; Bandyopadhyay, Dhrubajyoti; Isath, Ameesh; Gupta, Rahul; Hajra, Adrija; Shrivastav, Rishi; Virani, Salim S; Fonarow, Gregg C; Lavie, Carl J; Naidu, Srihari S.
  • Goel A; Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY. Electronic address: dr.akshaygoel@gmail.com.
  • Malik AH; Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
  • Bandyopadhyay D; Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
  • Isath A; Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
  • Gupta R; Lehigh Valley Heart Institute, Lehigh Valley Health Network, Allentown, PA.
  • Hajra A; Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY.
  • Shrivastav R; Icahn School of Medicine at Mount Sinai, New York, NY.
  • Virani SS; Baylor College of Medicine, Houston, TX.
  • Fonarow GC; University of California, Los Angeles, CA.
  • Lavie CJ; John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA.
  • Naidu SS; Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY.
Curr Probl Cardiol ; 48(4): 101547, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2260805
ABSTRACT
Patients with ST-segment elevation myocardial infarction (STEMI) and concurrent coronavirus disease 2019 (COVID-19) have been reported to have poor outcomes. However, previous studies are small and limited. The National Inpatient Sample database for the year 2020 was queried to identify all adult hospitalizations with a primary diagnosis of STEMI, with and without concurrent COVID-19. A 11 propensity score matching was performed. A total of 159,890 hospitalizations with a primary diagnosis of STEMI were identified. Of these, 2210 (1.38%) had concurrent COVID-19. After propensity matching, STEMI patients with concurrent COVID-19 had a significantly higher mortality (17.8% vs 9.1%, OR 1.96, P< 0.001), lower likelihood to receive same-day percutaneous coronary intervention (PCI) (63.6% vs 70.6%, P = 0.019), with a trend towards lower overall PCI (74.9% vs 80.2%, P = 0.057) and significantly lower coronary artery bypass grafting) (3.0% vs 6.8%, P = 0.008) prior to discharge, compared with STEMI patients without COVID-19. The prevalence of cardiogenic shock, need for mechanical circulatory support, extracorporeal membrane oxygenation, cardiac arrest, acute kidney injury (AKI), dialysis, major bleeding and stroke were not significantly different between the groups. COVID-19-positive STEMI patients who received same-day PCI had significantly lower odds of in-hospital mortality (adjusted OR 0.42, 95% CI 0.20-0.85, P = 0.017). STEMI patients with concurrent COVID-19 infection had a significantly higher (almost 2 times) in-hospital mortality, and lower likelihood of receiving same-day PCI, overall (any-day) PCI, and CABG during their admission, compared with STEMI patients without COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Percutaneous Coronary Intervention / ST Elevation Myocardial Infarction / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Curr Probl Cardiol Year: 2023 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Percutaneous Coronary Intervention / ST Elevation Myocardial Infarction / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Curr Probl Cardiol Year: 2023 Document Type: Article