Immunomodulatory meaning of diet and COVID-19
Medycyna Oglna i Nauki o Zdrowiu
; 28(4):286-294, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2261352
ABSTRACT
Introduction and objective:
The latest scientific reports showed that there is a relationship between the state of the gastrointestinal tract and the immune system, and the incidence of COVID-19. Diet can exert an immunomodulatory effect and regulate the immune response of an organism. The aim of the review is to show the effects of immunomodulators contained/supplemented in a diet on the infection SARS-CoV-2 and the course of COVID-19. Reviewmethods:
The literature review was conducted using PubMed, Google Scholar and the Medline database. Abbreviated description of the state of knowledgeRegular vitamin D supplementation significantly reduces the risk of respiratory infection with SARS-CoV-2;vitamin C may inhibit the expression of the ACE2 receptor in human small alveolar epithelial cells and limit the penetration of SARS-CoV-2;reduced iron levels predispose people to severe COVID-19 symptoms;selenium deficiency may be responsible for a decreased level of antibodies and NK cell cytotoxicity. Alo.. vera isolated polysaccharides strengthens the immune system;the quercetin and ellagic acid in combination with virus proteins show potential antiviral activity against SARSCoV- 2. Subsequently, adaptogens, ginger, echinacea and curcumin - showed anti-inflammatory effects. Also, the optimal composition of the gut microbiota improved/maintained the integrity of the lymphoid tissue found in the gastrointestinal tract (GALT) and the functioning of the gut-pulmonary axis.Summary:
Natural immunomodulators may be a relatively safe therapeutic option in patients during the course of COVID-19, but there are still no official recommendations for their practical use in therapy. It should be emphasized that there is a need for further scientific research into the mechanisms of action and efficacy of phytotherapy in the context of the effectiveness of plant-based immunostimulants in alleviating the course of COVID-19 disease.
Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210], Nutrition related Disorders and Therapeutic Nutrition [VV130], Non-communicable Human Diseases and Injuries [VV600], Human Immunology and Allergology [VV055], immunomodulatory properties, human diseases, coronavirus disease 2019, immune system, viral diseases, immune response, immunological deficiency, diet, vitamin D, vitamin supplements, iron, trace elements, quercetin, ginger, curcumin, antiinflammatory properties, efficacy, digestive tract, disease course, immunology, pathogenesis, physiopathology, selenium, cohort studies, polysaccharides, zinc, man, Severe acute respiratory syndrome coronavirus 2, Aloe vera, Echinacea, Zingiber, Homo, Hominidae, primates, mammals, vertebrates, Chordata, animals, eukaryotes, Severe acute respiratory syndrome-related coronavirus, Betacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, Aloe, Xanthorrhoeaceae, Asparagales, monocotyledons, angiosperms, Spermatophyta, plants, Asteraceae, Asterales, eudicots, Zingiberaceae, Zingiberales, commelinids, SARS-CoV-2, viral infections, immunity reactions, immunological reactions, immune deficiency, immunodeficiency, microelements, anti-inflammatory properties, gastrointestinal tract, disease progression, pathophysiology, complex carbohydrates
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Medycyna Oglna i Nauki o Zdrowiu
Year:
2022
Document Type:
Article
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