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COVID-19 patients : predictive factors for home therapy oxygen
European Respiratory Journal Conference: European Respiratory Society International Congress, ERS ; 60(Supplement 66), 2022.
Article in English | EMBASE | ID: covidwho-2261452
ABSTRACT
Bakground COVID-19 patients mostly experience a favorable evolution of the disease. However patients without acute respiratory distress syndrome (ARDS) but in need of long term oxygen therapy have received much less attention. Aim(s) To determine the predictive factors of home therapy oxygen after hospital discharge for COVID19 pneumonia. Method(s) We conducted a retrospective study including with laboratory-confirmed COVID-19 infection hospitalized in the pulmonology department of the military hospital of Tunisia. We divided our patients into two groups the first group (16 patients, 7%) requiring long term oxygen therapy (G1), the second group discharged without oxygen (G2). Result(s) A total of 245 patients were enrolled in the study. The median age was 61 years old. The majority of the population were male (77%). Home therapy oxygen needs were not correlated with the scanner degree impairment upon admission as well as the duration and posology of corticotherapy during hospitalization. It was significatively associated with an increased hospital stay (r=0,314;p=<0,001). Predictive home oxygen therapy factors were patients with extensive fibrotic-like changes on lung CT scan upon admission (r=0.223;p=0.04), heightened procalcitonin (PCT) level (p=0.009). No correlation was found with, intensive care transfer or other biomarkers levels. Independent predictive factors of long term oxygen therapy prescription were increased hospital stay (ORa = 1.092 [1.026-1.164], p = 0.006) and pulmonary fibrosis on lung CT scan upon admission (ORa = 17.405 [2.353-128.721], p = 0.005). Conclusion(s) Increased hospital stay and extensive fibrotic-like on lung CT scan initial should be used to identify patients in need for adjunctive therapy.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: European Respiratory Journal Conference: European Respiratory Society International Congress, ERS Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: European Respiratory Journal Conference: European Respiratory Society International Congress, ERS Year: 2022 Document Type: Article